2-(2-methyl-2-indolyl)acetic acid ethyl ester

2-(2-methyl-2-indolyl)acetic acid ethyl ester - Names and Identifiers

Name	2-甲基-3-吲哚乙酸乙酯
Synonyms	Nsc289352 Ethyl 2-methylindoleacetate ETHYL 2-METHYL-3-INDOLEACETATE ethyl 2-(2-methyl-1H-indol-3-yl)acetate 2-(2-methyl-2-indolyl)acetic acid ethyl ester 1H-Indole-3-acetic acid, 2-Methyl-, ethyl ester
CAS	21909-49-9

2-(2-methyl-2-indolyl)acetic acid ethyl ester - Physico-chemical Properties

Molecular Formula	C13H15NO2
Molar Mass	217.26
Density	1.11 g/mL at 25 °C (lit.)
Melting Point	95 °C(Solv: ethyl ether (60-29-7))
Boling Point	195-196 °C/3.5 mmHg (lit.)
Flash Point	>230°F
pKa	17.27±0.30(Predicted)
Refractive Index	n20/D 1.571(lit.)

2-(2-methyl-2-indolyl)acetic acid ethyl ester - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3

2-(2-methyl-2-indolyl)acetic acid ethyl ester - Introduction

Ethyl 2-methyl-3-indolyl acetate (also known as MIE) is an organic compound with the chemical formula C12H13NO2. The following is a brief description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Colorless or light yellow liquid
-Density: Approximately 1.10 g/mL
-Boiling point: about 270-275°C
-Melting point: approximately -25°C
-Solubility: Soluble in organic solvents such as alcohols and ethers

Use:
- 2-methyl -3-indole ethyl acetate is widely used in the field of medicine, as an important compound intermediate. It is the raw material of enzyme inhibitors, commonly used in the synthesis of anti-tumor drugs and antipsychotic drugs.
-In addition, it can also be used in organic synthesis reactions and is often used as a reagent in organic chemistry laboratories.

Preparation Method:
The common preparation method of -2-methyl -3-indole ethyl acetate is through the reaction of 2-methyl indole and ethyl bromoacetate.

Safety Information:
- 2-methyl -3-indole ethyl acetate specific safety information requires reference to its safety data sheet (Safety Data Sheet,SDS). When using and handling the compound, relevant safety practices should be observed to ensure the safety of personnel.

Last Update：2024-04-09 20:52:54